You have few options:
 
If your sound card is supported in Dos you'll need to load Dos Drivers onto your boot disk. Can't tell you how to do this specifically because every sound card is different (contact Sound card manufacturer or website for this).
Alternately you could run it in a virtual computer. Use Virtual PC or VMware as both will emulate an entire computer. Of course you will need to load Dos (ie have the Dos installation disks). You could also boot the virtual PC with a Win98 setup disk and format using the /s switch to make the virtual hard drive bootable.
 
Hope this helps.

Try VDMSound.

Try putting the program in compatibility mode by right-clicking the application go run in windows 98 or Me.............. hey its worth a shot

First you need:
1)LBA(doesnt have to be original game)
2)DOSbox(search Google)
3)No-CD crack(if you cant find ask me)
 
Install the game to a C:\ directory(like C:\LBA)
Open and type in DOSbox
mount C C:/LBA
then just type C: (then you should have a C instead of Z)
(if you have the game launching file in another folder in LBA folder)type cd foldername(like cd LBAgame)[cd=change directory]
then type the file that opens LBA(some have setup.exe and some LBA.exe)[if you have a crack then it should be Relent.exe)
If your game doesnt start, then in install or setup choose no sound and no speech.
 
Your game could be running slow in DOSbox so you need to find your best frameskip and cpu cycles.
ctrl+F12 increase cpu cycles (11000 worked best for me)
ctrl+F8 increase frameskip (10 was best for me)
If you have any questions dont hesitate to ask.

Hello
Yes, I'm looking for the LBA 1 No CD crack... If anyone has it please e-mail me to darkwave90@yahoo.ca thx!

I have the same problem, i need the crack, i have PM you about it too,
 
So if anyone have it, mail it for me!