AMD has released AMD Radeon Software Crimson Edition 16.5.3

Radeon Software Crimson Edition is AMD's revolutionary new graphics software that delivers redesigned functionality, supercharged graphics performance, remarkable new features, and innovation that redefines the overall user experience. Every Radeon Software release strives to deliver new features, better performance and stability improvements.

Radeon Software Crimson Edition 16.5.3 Highlights
Support for:
Total War: Warhammer
Overwatch
Dota2 (with Vulkan API)

New AMD Crossfire profile available for:
Total War: Warhammer
Overwatch

Fixed Issues
Fallout 4 may experience minor stuttering in AMD Crossfire technology mode
Radeon Settings may be removed from the system if the Radeon Software installer is launched while Radeon Settings is open.
Radeon Settings "Additional Settings" option may intermittently fail to launch.
Users in Quad AMD Crossfire technology configurations may be unable to re-enable AMD Crossfire mode when using the global AMD Crossfire option in the "Gaming" tab and toggling it from on to off.
Some game textures in The Division exhibit flickering in AMD Crossfire mode.
Intermittent stability issues with Intel Skull Canyon NUC (NUC6i7KYK) using AMD XConnect Technology are no longer observed.
Safe unplugging for AMD XConnect Technology no longer results in a random BSOD.

Known Issues
A few game titles may fail to launch or crash if the AMD Gaming Evolved overlay is enabled. A temporary workaround is to disable the AMD Gaming Evolved "In Game Overlay".
Total War: Warhammer may experience stuttering in AMD Crossfire technology mode if the AMD Gaming Evolved App or Plays.Tv is running in the background. A workaround is to disable the AMD Gaming Evolved and Plays.Tv applications.
The Division may hang when using Quad AMD Crossfire technology. As a workaround users are recommended to disable AMD Crossfire technology mode.
Heroes of the Storm may experience flickering in AMD Crossfire technology mode.
The AMD Crossfire technology mode options in Radeon Settings may not take effect on Origin or Uplay applications.
Forza Motorsport 6: Apex may exhibit brightness flickering when using AMD FreeSync technology.
Frame Rate Target Control gaming profiles may fail to enable for some games.
Catalyst Install Manager unable to detect the display driver while​ uninstallation.

  AMD Radeon Software Crimson Edition 16.5.3